NADH feeds your mitochondria with the electrons needed to make ATP — the energy your body actually uses. More efficient ATP → more consistent daytime energy and mental clarity. Unlike caffeine, this is non-stimulant support.
Science: NADH donates electrons into Complex I of the mitochondrial chain (mechanism of ATP generation)
When routines flip (red-eye flights, time-zones), sublingual stabilized NADH in research improved cognitive performance and reduced sleepiness the morning after travel. Capsules are great for a steady daily routine; for travel days, morning timing matters.
Science: Randomized, double-blind, placebo-controlled trial in travelers; NASA technical report concludes sublingual stabilized NADH was a suitable short-term countermeasure for jet lag cognitive effects.
Research:
By supporting mitochondrial ATP in neurons, NADH helps you stay clear-headed and “switched on” without stimulants. Under sleep-loss contexts like jet lag, small RCTs show measurable cognitive benefits.
Science: Cognitive performance improvements under jet-lag/sleep-debt conditions; summary of small DB-PC trials. PubMedEBSCO
For people struggling with persistent tiredness, co-supplementation NADH + CoQ10 (8–12 weeks) improved fatigue, sleep quality i/ili exercise-test markers u randomiziranim, dvostruko slijepim ispitivanjima. (Napomena: studije su rađene u CFS/ME — specifičnoj populaciji.)
Science: RCTs in ME/CFS: 8-week and 12-week double-blind trials with CoQ10+NADH improved fatigue-related outcomes vs placebo.